Research groups immunology (Venusberg)

 

Institute of Molecular Medicine and Experimental Immunology (IMMEI)

Life and Medical Sciences Insitute (LIMES)

Insitute of Innate Immunity (III)

 

Institute of molecular psychiatry

  1. Neuroinflammation and aging

 

Institute of clinical chemistry and clinical pharmacology

  1. Recognition of viruses, T-cell immunity
  2. Participation of non-immune cells in innate immune sensing, nucleic acid sensing in CNS
  3. RIG-I, TLR-sensing
  4. Inflammatory response in cancer
  5. Innate immune response to viruses
  6. RIG-I sensing
  7. Metabolism of ILCs

 

Department of experimental dermatology

  1. Role of T-cells in melanoma, neuro-immunology of the skin, autoimmune conditions

 

UKB Medical clinic 1

  1. DC-based-vaccines for tumor treatment
  2. Role of CD4+ cells in HCV-pathogenesis
  3. ILC activation in HIV and liver fibrosis

 

UKB Hematology and Oncology

  1. Systemic autoimmunity; cancer immunity; myeloid cells
  2. Treg-cells in tumor development and graft-versus-host-disease
  3. Nosocomial infections

 

UKB Dermatology clinic

  1. Pathogenesis of atopical dermatitis (function of IgE-receptors, basophils and mast cells): AG Novak and AG Bieber
  2. Dermato-oncology
  3. Mechanisms of IFN-induction, role in autoimmunity, anti-bacterial and anti-viral response

 

UKB eye hospital

  1. Macrophages and their role in tumor biology
  2. Pathogenesis of age-related macular degeneration (NLRP3 inflammasome activation, role of inflammatory cytokines)
  3. Function of Siglecs and sialic acid in neurodegeneration and neural regeneration

 

UKB surgical department

  1. Cellular and molecular mechanisms of gastro-intestinal infection

 

UKB heart center

  1. Vascular inflammation, activation of NLRP3-inflammasome, endothelial dysfunction
  2. COPD, asthma, lung fibrosis (AG Pneumologie)

 

DZNE

  1. Characterization of regulatory T cells, T cell differentiation and T cell exhaustion
  2. Epidemiology of neurodegenerative and other age-related diseases.
  3. Immune regulation in aging brain
  4. Role of microglia in Alzheimer’s disease, imaging
  5. Microglia and neuroinflammation
  6. Neuroinflammation in Alzheimer’s disease

 

Institute of Medical Microbiology, Immunology and Parasitology

  1. T-cell mediated immunosuppression in parasitic diseases, anti-Wolbachia-therapy development
  2. Role of Wolbachia bacteria in life cycles of filarial nematodes Wuchereria bancrofti, Brugia malayi and Onchocerca volvulus
  3. Helminth-induced immunomodulation in the host
  4. Cerebral malaria